About Us

Alpha-1 Research Program

The Alpha-1 Research Program was established at the University of Florida in 1998 through the Alpha-1 Foundation, and under the guidance of Dr. Mark Brantly. In 2024, Dr. Karina Serban was appointed Program Director and currently oversees all aspects from clinical trials to bench research and partnership projects within the medical and scientific Alpha-1 communities. Our partnership with Drs. Virginia Clark and Jorge Lascano, specializing in Alpha-1 related liver and lung disease, brings a full patient-centered approach to developing a cure for Alpha-1 Antitrypsin Deficiency.

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Mission

Our mission is to improve the lives of alpha-1 antitrypsin individuals and their families through research and service by developing new therapies that target lung and liver disease associated with alpha-1 antitrypsin deficiency using a combination of basic and clinical research.

Services and Resources

The Alpha-1 Research Program resources and services include: