Regina A Oshins,
Scientific Laboratory Manager
Department:
MD-PULMONARY MEDICINE
Business Phone:
(352) 273-8737
Business Email:
regina.oshins@medicine.ufl.edu
Publications
2024
Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Hepatology communications.
8(2)
[DOI] 10.1097/HC9.0000000000000370.
[PMID] 38285890.
2023
Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function.
Respiratory research.
24(1)
[DOI] 10.1186/s12931-023-02605-0.
[PMID] 38082274.
2023
Novel SERPINA1 Alleles Identified through a Large Alpha-1 Antitrypsin Deficiency Screening Program and Review of Known Variants.
Chronic obstructive pulmonary diseases (Miami, Fla.).
10(1):7-21
[DOI] 10.15326/jcopdf.2022.0321.
[PMID] 36367950.
2022
Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency.
American journal of physiology. Gastrointestinal and liver physiology.
323(6):G594-G608
[DOI] 10.1152/ajpgi.00207.2022.
[PMID] 36256438.
2022
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Respiratory research.
23(1)
[DOI] 10.1186/s12931-022-02161-z.
[PMID] 36068572.
2022
Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.
PloS one.
17(9)
[DOI] 10.1371/journal.pone.0274427.
[PMID] 36084115.
2022
Reply.
Hepatology communications.
6(12)
[DOI] 10.1002/hep4.2084.
[PMID] 36017787.
2022
The unfolded protein response to PI*Z alpha-1 antitrypsin in human hepatocellular and murine models.
Hepatology communications.
6(9):2354-2367
[DOI] 10.1002/hep4.1997.
[PMID] 35621045.
2021
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
International journal of molecular sciences.
22(24)
[DOI] 10.3390/ijms222413255.
[PMID] 34948056.
2020
Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils.
Frontiers in immunology.
11
[DOI] 10.3389/fimmu.2020.574410.
[PMID] 33329539.
2020
Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo.
Cell communication and signaling : CCS.
18(1)
[DOI] 10.1186/s12964-020-00648-0.
[PMID] 32887613.
2020
Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway.
Scientific reports.
10(1)
[DOI] 10.1038/s41598-020-72667-3.
[PMID] 32981934.
2019
A Novel Small Molecule Inhibits Intrahepatocellular Accumulation of Z-Variant Alpha 1-Antitrypsin In Vitro and In Vivo.
Cells.
8(12)
[DOI] 10.3390/cells8121586.
[PMID] 31817705.
2019
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α1-antitrypsin disposal
Journal of Biological Chemistry.
294(16):6240-6252
[DOI] 10.1074/jbc.RA118.006142.
[PMID] 30833329.
2019
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α1-antitrypsin disposal
Journal of Biological Chemistry.
294(16):6240-6252
2013
Development, validation and use of ELISA for antibodies to human alpha-1 antitrypsin.
Journal of immunological methods.
388(1-2):18-24
[DOI] 10.1016/j.jim.2012.11.008.
[PMID] 23195820.
2010
Identification and preliminary characterization of ubiquitin C terminal hydrolase 1 (UCHL1) as a biomarker of neuronal loss in aneurysmal subarachnoid hemorrhage
Journal of Neuroscience Research.
88(7):1475-1484
2010
Identification and preliminary characterization of ubiquitin C terminal hydrolase 1 (UCHL1) as a biomarker of neuronal loss in aneurysmal subarachnoid hemorrhage.
Journal of neuroscience research.
88(7):1475-84
[DOI] 10.1002/jnr.22323.
[PMID] 20077430.
2008
Detection of phosphorylated NF-H in the cerebrospinal fluid and blood of aneurysmal subarachnoid hemorrhage patients.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
28(6):1261-71
[DOI] 10.1038/jcbfm.2008.12.
[PMID] 18319731.
2007
Alpha-II spectrin breakdown products in aneurysmal subarachnoid hemorrhage: a novel biomarker of proteolytic injury.
Journal of neurosurgery.
107(4):792-6
[PMID] 17937225.
2005
A multidimensional differential proteomic platform using dual-phase ion-exchange chromatography-polyacrylamide gel electrophoresis/reversed-phase liquid chromatography tandem mass spectrometry.
Analytical chemistry.
77(15):4836-45
[PMID] 16053296.
2005
Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry
Journal of Neurotrauma.
22(6):629-644
Education
Bachelor of Science, Chemical Engineering
2003
·
University of Florida
Contact Details
Phones:
- Business:
- (352) 273-8737
Emails:
- Business:
- regina.oshins@medicine.ufl.edu
Addresses:
- Business Mailing:
-
BOX 100225
1600 SW ARCHER RD RM M330
GAINESVILLE FL 32610 - Business Street:
-
JHMHSC
GAINESVILLE FL 326100001